The Effects of Boceprevir and Telaprevir on the Pharmacokinetics of Maraviroc: An Open-Label, Fixed-Sequence Study in Healthy Volunteers

OBJECTIVE: To evaluate the effects of boceprevir (BOC) and telaprevir (TVR) on the pharmacokinetics (PK) of maraviroc (MVC) in healthy volunteers. METHODS: In this open-label, fixed-sequence study, 14 volunteers received MVC 150 mg twice daily alone for 5 days (period 1), followed by MVC + BOC 800 m...

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Detalles Bibliográficos
Autores principales: Vourvahis, Manoli, Plotka, Anna, Kantaridis, Constantino, Fang, Annie, Heera, Jayvant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984012/
https://www.ncbi.nlm.nih.gov/pubmed/24346637
http://dx.doi.org/10.1097/QAI.0000000000000090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984012/
https://www.ncbi.nlm.nih.gov/pubmed/24346637
http://dx.doi.org/10.1097/QAI.0000000000000090

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