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Single Nucleotide Polymorphism (SNP)-Strings: An Alternative Method for Assessing Genetic Associations
BACKGROUND: Genome-wide association studies (GWAS) identify disease-associations for single-nucleotide-polymorphisms (SNPs) from scattered genomic-locations. However, SNPs frequently reside on several different SNP-haplotypes, only some of which may be disease-associated. This circumstance lowers th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984082/ https://www.ncbi.nlm.nih.gov/pubmed/24727690 http://dx.doi.org/10.1371/journal.pone.0090034 |