Endothelin A Receptor Antagonism Enhances Inhibitory Effects of Anti-Ganglioside GD2 Monoclonal Antibody on Invasiveness and Viability of Human Osteosarcoma Cells

Endothelin-1 (ET-1)/endothelin A receptor (ETAR) signaling is important for osteosarcoma (OS) progression. Monoclonal antibodies (mAbs) targeting ganglioside GD2 reportedly inhibit tumor cell viability independent of the immune system. A recent study suggests that ganglioside GD2 may play an importa...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Wu, Yi, Zhou, Yu, Peng, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984094/
https://www.ncbi.nlm.nih.gov/pubmed/24727660
http://dx.doi.org/10.1371/journal.pone.0093576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984094/
https://www.ncbi.nlm.nih.gov/pubmed/24727660
http://dx.doi.org/10.1371/journal.pone.0093576

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