Cargando…

miR-34a Modulates Angiotensin II-Induced Myocardial Hypertrophy by Direct Inhibition of ATG9A Expression and Autophagic Activity

Cardiac hypertrophy is characterized by thickening myocardium and decreasing in heart chamber volume in response to mechanical or pathological stress, but the underlying molecular mechanisms remain to be defined. This study investigated altered miRNA expression and autophagic activity in pathogenesi...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jionghua, Sun, Wen, Huang, He, Ye, Jing, Pan, Wei, Zhong, Yun, Cheng, Chuanfang, You, Xiangyu, Liu, Benrong, Xiong, Longgen, Liu, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984180/
https://www.ncbi.nlm.nih.gov/pubmed/24728149
http://dx.doi.org/10.1371/journal.pone.0094382