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PDZK1 and NHERF1 Regulate the Function of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) by Modulating Its Subcellular Trafficking and Stability

The human organic anion transporting polypeptide 1A2 (OATP1A2) is an important membrane protein that mediates the cellular influx of various substances including drugs. Previous studies have shown that PDZ-domain containing proteins, especially PDZK1 and NHERF1, regulate the function of related memb...

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Detalles Bibliográficos
Autores principales: Zheng, Jian, Chan, Ting, Cheung, Florence Shin Gee, Zhu, Ling, Murray, Michael, Zhou, Fanfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984249/
https://www.ncbi.nlm.nih.gov/pubmed/24728453
http://dx.doi.org/10.1371/journal.pone.0094712