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PDZK1 and NHERF1 Regulate the Function of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) by Modulating Its Subcellular Trafficking and Stability
The human organic anion transporting polypeptide 1A2 (OATP1A2) is an important membrane protein that mediates the cellular influx of various substances including drugs. Previous studies have shown that PDZ-domain containing proteins, especially PDZK1 and NHERF1, regulate the function of related memb...
Autores principales: | Zheng, Jian, Chan, Ting, Cheung, Florence Shin Gee, Zhu, Ling, Murray, Michael, Zhou, Fanfan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984249/ https://www.ncbi.nlm.nih.gov/pubmed/24728453 http://dx.doi.org/10.1371/journal.pone.0094712 |
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