Combined effect of hyperfiltration and renin angiotensin system activation on development of chronic kidney disease in diabetic db/db mice

BACKGROUND: Hypertension is a major risk factor for renal disease progression. However, the mechanisms by which hypertension aggravates the effects of diabetes on the kidney are incompletely understood. We tested the hypothesis that renovascular hypertension accelerates angiotensin-II-dependent kidn...

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Detalles Bibliográficos
Autores principales: Hartono, Stella P, Knudsen, Bruce E, Lerman, Lilach O, Textor, Stephen C, Grande, Joseph P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984262/
https://www.ncbi.nlm.nih.gov/pubmed/24708836
http://dx.doi.org/10.1186/1471-2369-15-58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984262/
https://www.ncbi.nlm.nih.gov/pubmed/24708836
http://dx.doi.org/10.1186/1471-2369-15-58

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