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Evolution of the F-Box Gene Family in Euarchontoglires: Gene Number Variation and Selection Patterns

F-box proteins are substrate adaptors used by the SKP1–CUL1–F-box protein (SCF) complex, a type of E3 ubiquitin ligase complex in the ubiquitin proteasome system (UPS). SCF-mediated ubiquitylation regulates proteolysis of hundreds of cellular proteins involved in key signaling and disease systems. H...

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Detalles Bibliográficos
Autores principales: Wang, Ailan, Fu, Mingchuan, Jiang, Xiaoqian, Mao, Yuanhui, Li, Xiangchen, Tao, Shiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984280/
https://www.ncbi.nlm.nih.gov/pubmed/24727786
http://dx.doi.org/10.1371/journal.pone.0094899