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A remarkable activity of human leukotriene A(4) hydrolase (LTA4H) toward unnatural amino acids

Leukotriene A(4) hydrolase (LTA4H––EC 3.3.2.6) is a bifunctional zinc metalloenzyme, which processes LTA(4) through an epoxide hydrolase activity and is also able to trim one amino acid at a time from N-terminal peptidic substrates via its aminopeptidase activity. In this report, we have utilized a...

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Detalles Bibliográficos
Autores principales: Byzia, Anna, Haeggström, Jesper Z., Salvesen, Guy S., Drag, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984412/
https://www.ncbi.nlm.nih.gov/pubmed/24573245
http://dx.doi.org/10.1007/s00726-014-1694-2