Maternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice

BACKGROUND: The adverse effects on offspring of diabetic and/or obese mothers can be passed to the next generation. However, the mechanisms behind this are still unclear. Epigenetics may play a key role during this process. METHODS: To confirm the hypothesis, we investigated the DNA methylation of s...

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Detalles Bibliográficos
Autores principales: Ge, Zhao-Jia, Liang, Qiu-Xia, Hou, Yi, Han, Zhi-Ming, Schatten, Heide, Sun, Qing-Yuan, Zhang, Cui-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984639/
https://www.ncbi.nlm.nih.gov/pubmed/24721882
http://dx.doi.org/10.1186/1477-7827-12-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984639/
https://www.ncbi.nlm.nih.gov/pubmed/24721882
http://dx.doi.org/10.1186/1477-7827-12-29

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