Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates

Intragenic deletion is the most common form of activating mutation among receptor tyrosine kinases (RTK) in glioblastoma. However, these events are not detected by conventional DNA sequencing methods commonly utilized for tumor genotyping. To comprehensively assess the frequency, distribution, and e...

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Detalles Bibliográficos
Autores principales: Kastenhuber, Edward R., Huse, Jason T., Berman, Samuel H., Pedraza, Alicia, Zhang, Jianan, Suehara, Yoshiyuki, Viale, Agnes, Cavatore, Magali, Heguy, Adriana, Szerlip, Nicholas, Ladanyi, Marc, Brennan, Cameron W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984672/
https://www.ncbi.nlm.nih.gov/pubmed/24292886
http://dx.doi.org/10.1007/s00401-013-1217-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984672/
https://www.ncbi.nlm.nih.gov/pubmed/24292886
http://dx.doi.org/10.1007/s00401-013-1217-3

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