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Muscadine grape skin extract reverts snail-mediated epithelial mesenchymal transition via superoxide species in human prostate cancer cells

BACKGROUND: Snail transcription factor can induce epithelial-mesenchymal transition (EMT), associated with decreased cell adhesion-associated molecules like E-cadherin, increased mesenchymal markers like vimentin, leading to increased motility, invasion and metastasis. Muscadine grape skin extract (...

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Detalles Bibliográficos
Autores principales: Burton, Liza J, Barnett, Petrina, Smith, Basil, Arnold, Rebecca S, Hudson, Tamaro, Kundu, Kousik, Murthy, Niren, Odero-Marah, Valerie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984701/
https://www.ncbi.nlm.nih.gov/pubmed/24617993
http://dx.doi.org/10.1186/1472-6882-14-97