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(-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways
OBJECTIVE: In the wake of intracerebral hemorrhage (ICH), a devastating stroke with no effective treatment, hemoglobin/iron-induced oxidative injury leads to neuronal loss and poor neurologic outcomes. (-)-Epicatechin (EC), a brain-permeable flavanol that modulates redox/oxidative stress via the NF-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984761/ https://www.ncbi.nlm.nih.gov/pubmed/24741667 http://dx.doi.org/10.1002/acn3.54 |