Cargando…

(-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways

OBJECTIVE: In the wake of intracerebral hemorrhage (ICH), a devastating stroke with no effective treatment, hemoglobin/iron-induced oxidative injury leads to neuronal loss and poor neurologic outcomes. (-)-Epicatechin (EC), a brain-permeable flavanol that modulates redox/oxidative stress via the NF-...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Che-Feng, Cho, Suzy, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984761/
https://www.ncbi.nlm.nih.gov/pubmed/24741667
http://dx.doi.org/10.1002/acn3.54