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Multidrug Resistance 1 Gene Variants, Pesticide Exposure, and Increased Risk of DNA Damage

The P-glycoprotein, encoded by the multidrug resistance (MDR)1 gene, extrudes fat-soluble compounds to the extracellular environment. However, the DNA damage of pesticides in subjects with genetic variation in MDR1 has not been investigated. In this study, the comet assay was applied to examine the...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Chieh, Huang, Chun-Huang, Wu, Man-Tzu Marcie, Chou, Chia-Hsuan, Huang, Chia-Chen, Tseng, Tzu-Yen, Chang, Fang-Yu, Li, Ying-Ti, Tsai, Chun-Cheng, Wang, Tsung-Shing, Wong, Ruey-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984798/
https://www.ncbi.nlm.nih.gov/pubmed/24791009
http://dx.doi.org/10.1155/2014/965729