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Multidrug Resistance 1 Gene Variants, Pesticide Exposure, and Increased Risk of DNA Damage
The P-glycoprotein, encoded by the multidrug resistance (MDR)1 gene, extrudes fat-soluble compounds to the extracellular environment. However, the DNA damage of pesticides in subjects with genetic variation in MDR1 has not been investigated. In this study, the comet assay was applied to examine the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984798/ https://www.ncbi.nlm.nih.gov/pubmed/24791009 http://dx.doi.org/10.1155/2014/965729 |