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Therapeutic Approaches for Inhibition of Protein Aggregation in Huntington's Disease
Huntington's disease (HD) is a late-onset and progressive neurodegenerative disorder that is caused by aggregation of mutant huntingtin protein which contains expanded-polyglutamine. The molecular chaperones modulate the aggregation in early stage and known for the most potent protector of neur...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Society for Brain and Neural Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984955/ https://www.ncbi.nlm.nih.gov/pubmed/24737938 http://dx.doi.org/10.5607/en.2014.23.1.36 |