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Attenuated Glial K(+) Clearance Contributes to Long-Term Synaptic Potentiation Via Depolarizing GABA in Dorsal Horn Neurons of Rat Spinal Cord

It has been reported that long-term enhancement of superficial dorsal horn (DH(s)) excitatory synaptic transmission underlies central sensitization, secondary hyperalgesia, and persistent pain. We tested whether impaired clearance of K(+) and glutamate by glia in DH(s) may contribute to initiation a...

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Detalles Bibliográficos
Autores principales: Lee, Jaekwang, Favorov, Oleg V, Tommerdahl, Mark, Lee, C. Justin, Whitsel, Barry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984957/
https://www.ncbi.nlm.nih.gov/pubmed/24737940
http://dx.doi.org/10.5607/en.2014.23.1.53