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Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease
Alzheimer's disease (AD) is a complex disorder that affects the central nervous system causing a severe neurodegeneration. This pathology affects an increasing number of people worldwide due to the overall aging of the human population. In recent years SUMO protein modification has emerged as a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985012/ https://www.ncbi.nlm.nih.gov/pubmed/24778618 http://dx.doi.org/10.3389/fphar.2014.00063 |