Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model

Adult T cell leukemia (ATL) is a malignant lymphoproliferative disease caused by human T cell leukemia virus type I (HTLV-I). To develop an effective therapy against the disease, we have examined the oncolytic ability of an attenuated vaccinia virus (VV), LC16m8Δ (m8Δ), and an HTLV-I Tax-specific cy...

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Detalles Bibliográficos
Autores principales: Ohashi, Takashi, Nakamura, Takafumi, Kidokoro, Minoru, Zhang, Xianfeng, Shida, Hisatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985193/
https://www.ncbi.nlm.nih.gov/pubmed/24791004
http://dx.doi.org/10.1155/2014/902478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985193/
https://www.ncbi.nlm.nih.gov/pubmed/24791004
http://dx.doi.org/10.1155/2014/902478

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