Cargando…
Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model
Adult T cell leukemia (ATL) is a malignant lymphoproliferative disease caused by human T cell leukemia virus type I (HTLV-I). To develop an effective therapy against the disease, we have examined the oncolytic ability of an attenuated vaccinia virus (VV), LC16m8Δ (m8Δ), and an HTLV-I Tax-specific cy...
Autores principales: | Ohashi, Takashi, Nakamura, Takafumi, Kidokoro, Minoru, Zhang, Xianfeng, Shida, Hisatoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985193/ https://www.ncbi.nlm.nih.gov/pubmed/24791004 http://dx.doi.org/10.1155/2014/902478 |
Ejemplares similares
-
Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model
por: Ohashi, Takashi, et al.
Publicado: (2008) -
Functional impairment of Tax-specific but not CMV-specific CTLs in a minor population of asymptomatic HTLV-1-carriers
por: Hasegawa, Atsuhiko, et al.
Publicado: (2011) -
Vaccinia Virus LC16m8∆ as a Vaccine Vector for Clinical Applications
por: Kidokoro, Minoru, et al.
Publicado: (2014) -
Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity
por: Gauthier, Sonia, et al.
Publicado: (2008) -
Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach
por: de la Fuente, Cynthia, et al.
Publicado: (2006)