Cytochrome C and Caspase-3/7 are Involved in Mycophenolic Acid- Induced Apoptosis in Genetically Engineered PC12 Neuronal Cells Expressing the p53 gene

Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil. This study designed to investigate the mechanism of cytotoxicity of MPA on the genetically engineered PC12 Tet Off (PTO) neuronal cells with p53 gene. Alamar Blue (AB) reduction showed concentration-dependent cytotoxicity of...

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Detalles Bibliográficos
Autores principales: Malekinejad, Hassan, Moradi, Masumeh, Fink-Gremmels, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985263/
https://www.ncbi.nlm.nih.gov/pubmed/24734071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985263/
https://www.ncbi.nlm.nih.gov/pubmed/24734071

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