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Imaging an optogenetic pH sensor reveals that protons mediate lateral inhibition in the retina

The reciprocal synapse between photoreceptors and horizontal cells (HCs) underlies lateral inhibition and establishes the antagonistic center-surround receptive fields of retinal neurons, to enhance visual contrast. Despite decades of study, the signal mediating negative feedback from HCs to cones h...

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Detalles Bibliográficos
Autores principales: Wang, Tzu-Ming, Holzhausen, Lars C., Kramer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985427/
https://www.ncbi.nlm.nih.gov/pubmed/24441679
http://dx.doi.org/10.1038/nn.3627