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Identification and Characterization of Noncovalent Interactions That Drive Binding and Specificity in DD-Peptidases and β-Lactamases

[Image: see text] Bacterial resistance to standard (i.e., β-lactam-based) antibiotics has become a global pandemic. Simultaneously, research into the underlying causes of resistance has slowed substantially, although its importance is universally recognized. Key to unraveling critical details is cha...

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Detalles Bibliográficos
Autores principales: Hargis, Jacqueline C., Vankayala, Sai Lakshmana, White, Justin K., Woodcock, H. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985439/
https://www.ncbi.nlm.nih.gov/pubmed/24803854
http://dx.doi.org/10.1021/ct400968v