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Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery

[Image: see text] Aptamer–drug conjugates (ApDCs) are promising targeted drug delivery systems for reducing toxicity while increasing the efficacy of chemotherapy. However, current ApDC technologies suffer from problems caused by the complicated preparation and low controllability of drug–aptamer co...

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Detalles Bibliográficos
Autores principales: Wang, RuoWen, Zhu, Guizhi, Mei, Lei, Xie, Yan, Ma, Haibin, Ye, Mao, Qing, Feng-Ling, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985443/
https://www.ncbi.nlm.nih.gov/pubmed/24483627
http://dx.doi.org/10.1021/ja4117395