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High Temperature SELMA: Evolution of DNA-Supported Oligomannose Clusters Which Are Tightly Recognized by HIV bnAb 2G12
[Image: see text] SELMA (SELection with Modified Aptamers) is a directed evolution method which can be used to develop DNA-supported clusters of carbohydrates in which the geometry of clustering is optimized for strong recognition by a lectin of interest. Herein, we report a modification of SELMA wh...
Autores principales: | Temme, J. Sebastian, MacPherson, Iain S., DeCourcey, John F., Krauss, Isaac J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985446/ https://www.ncbi.nlm.nih.gov/pubmed/24446826 http://dx.doi.org/10.1021/ja411212q |
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