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The Transcriptional Complex Between the BCL2 i-Motif and hnRNP LL Is a Molecular Switch for Control of Gene Expression That Can Be Modulated by Small Molecules

[Image: see text] In a companion paper (DOI: 10.021/ja410934b) we demonstrate that the C-rich strand of the cis-regulatory element in the BCL2 promoter element is highly dynamic in nature and can form either an i-motif or a flexible hairpin. Under physiological conditions these two secondary DNA str...

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Detalles Bibliográficos
Autores principales: Kang, Hyun-Jin, Kendrick, Samantha, Hecht, Sidney M., Hurley, Laurence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985447/
https://www.ncbi.nlm.nih.gov/pubmed/24559432
http://dx.doi.org/10.1021/ja4109352