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Saccharomyces cerevisiae Thg1 Uses 5′-Pyrophosphate Removal To Control Addition of Nucleotides to tRNA(His)

[Image: see text] In eukaryotes, the tRNA(His) guanylyltransferase (Thg1) catalyzes 3′–5′ addition of a single guanosine residue to the −1 position (G(–1)) of tRNA(His), across from a highly conserved adenosine at position 73 (A(73)). After addition of G(–1), Thg1 removes pyrophosphate from the tRNA...

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Detalles Bibliográficos
Autores principales: Smith, Brian A., Jackman, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985462/
https://www.ncbi.nlm.nih.gov/pubmed/24548272
http://dx.doi.org/10.1021/bi4014648