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Thermodynamic and Phylogenetic Insights into hnRNP A1 Recognition of the HIV-1 Exon Splicing Silencer 3 Element

[Image: see text] Complete expression of the HIV-1 genome requires balanced usage of suboptimal splice sites. The 3′ acceptor site A7 (ssA7) is negatively regulated in part by an interaction between the host hnRNP A1 protein and a viral splicing silencer (ESS3). Binding of hnRNP A1 to ESS3 and other...

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Detalles Bibliográficos
Autores principales: Rollins, Carrie, Levengood, Jeffrey D., Rife, Brittany D., Salemi, Marco, Tolbert, Blanton S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985463/
https://www.ncbi.nlm.nih.gov/pubmed/24628426
http://dx.doi.org/10.1021/bi500180p