Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

[Image: see text] Ferrostatin-1 (Fer-1) inhibits ferroptosis, a form of regulated, oxidative, nonapoptotic cell death. We found that Fer-1 inhibited cell death in cellular models of Huntington’s disease (HD), periventricular leukomalacia (PVL), and kidney dysfunction; Fer-1 inhibited lipid peroxidat...

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Detalles Bibliográficos
Autores principales: Skouta, Rachid, Dixon, Scott J., Wang, Jianlin, Dunn, Denise E., Orman, Marina, Shimada, Kenichi, Rosenberg, Paul A., Lo, Donald C., Weinberg, Joel M., Linkermann, Andreas, Stockwell, Brent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985476/
https://www.ncbi.nlm.nih.gov/pubmed/24592866
http://dx.doi.org/10.1021/ja411006a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985476/
https://www.ncbi.nlm.nih.gov/pubmed/24592866
http://dx.doi.org/10.1021/ja411006a

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