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Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
[Image: see text] Ferrostatin-1 (Fer-1) inhibits ferroptosis, a form of regulated, oxidative, nonapoptotic cell death. We found that Fer-1 inhibited cell death in cellular models of Huntington’s disease (HD), periventricular leukomalacia (PVL), and kidney dysfunction; Fer-1 inhibited lipid peroxidat...
Autores principales: | Skouta, Rachid, Dixon, Scott J., Wang, Jianlin, Dunn, Denise E., Orman, Marina, Shimada, Kenichi, Rosenberg, Paul A., Lo, Donald C., Weinberg, Joel M., Linkermann, Andreas, Stockwell, Brent R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985476/ https://www.ncbi.nlm.nih.gov/pubmed/24592866 http://dx.doi.org/10.1021/ja411006a |
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