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Dph3 Is an Electron Donor for Dph1-Dph2 in the First Step of Eukaryotic Diphthamide Biosynthesis

[Image: see text] Diphthamide, the target of diphtheria toxin, is a unique posttranslational modification on translation elongation factor 2 (EF2) in archaea and eukaryotes. The biosynthesis of diphthamide was proposed to involve three steps. The first step is the transfer of the 3-amino-3-carboxypr...

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Detalles Bibliográficos
Autores principales: Dong, Min, Su, Xiaoyang, Dzikovski, Boris, Dando, Emily E., Zhu, Xuling, Du, Jintang, Freed, Jack H., Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985478/
https://www.ncbi.nlm.nih.gov/pubmed/24422557
http://dx.doi.org/10.1021/ja4118957