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Design and Synthesis of Heterocyclic Cations for Specific DNA Recognition: From AT-Rich to Mixed-Base-Pair DNA Sequences
[Image: see text] The compounds synthesized in this research were designed with the goal of establishing a new paradigm for mixed-base-pair DNA sequence-specific recognition. The design scheme starts with a cell-permeable heterocyclic cation that binds to AT base pair sites in the DNA minor groove....
| Autores principales: | , , , , |
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| Format: | Online Artículo Texto |
| Sprog: | English |
| Udgivet: |
American Chemical
Society
2014
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| Online adgang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985508/ https://www.ncbi.nlm.nih.gov/pubmed/24422528 http://dx.doi.org/10.1021/jo402599s |