Design and Synthesis of Heterocyclic Cations for Specific DNA Recognition: From AT-Rich to Mixed-Base-Pair DNA Sequences

[Image: see text] The compounds synthesized in this research were designed with the goal of establishing a new paradigm for mixed-base-pair DNA sequence-specific recognition. The design scheme starts with a cell-permeable heterocyclic cation that binds to AT base pair sites in the DNA minor groove....

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Detalles Bibliográficos
Autores principales: Chai, Yun, Paul, Ananya, Rettig, Michael, Wilson, W. David, Boykin, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985508/
https://www.ncbi.nlm.nih.gov/pubmed/24422528
http://dx.doi.org/10.1021/jo402599s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985508/
https://www.ncbi.nlm.nih.gov/pubmed/24422528
http://dx.doi.org/10.1021/jo402599s

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