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Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5γ2 signaling pathway

BACKGROUND: Vasculogenic mimicry (VM) is a novel tumor blood supply in some highly aggressive malignant tumors. Recently, we reported VM existed in gallbladder carcinomas (GBCs) and the formation of the special passage through the activation of the PI3K/MMPs/Ln-5γ2 signaling pathway. GBC is a highly...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Tao, Sun, Wei, Zhang, Wen-Zhong, Ge, Chun-Yan, Liu, Zhong-Yan, Zhao, Ze-Ming, Lu, Xing-Sui, Fan, Yue-Zu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985599/
https://www.ncbi.nlm.nih.gov/pubmed/24628713
http://dx.doi.org/10.1186/1471-2407-14-193