Differential RISC association of endogenous human microRNAs predicts their inhibitory potential

It has previously been assumed that the generally high stability of microRNAs (miRNAs) reflects their tight association with Argonaute (Ago) proteins, essential components of the RNA-induced silencing complex (RISC). However, recent data have suggested that the majority of mature miRNAs are not, in...

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Detalles Bibliográficos
Autores principales: Flores, Omar, Kennedy, Edward M., Skalsky, Rebecca L., Cullen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985621/
https://www.ncbi.nlm.nih.gov/pubmed/24464996
http://dx.doi.org/10.1093/nar/gkt1393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985621/
https://www.ncbi.nlm.nih.gov/pubmed/24464996
http://dx.doi.org/10.1093/nar/gkt1393

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