Cargando…
Differential RISC association of endogenous human microRNAs predicts their inhibitory potential
It has previously been assumed that the generally high stability of microRNAs (miRNAs) reflects their tight association with Argonaute (Ago) proteins, essential components of the RNA-induced silencing complex (RISC). However, recent data have suggested that the majority of mature miRNAs are not, in...
Autores principales: | Flores, Omar, Kennedy, Edward M., Skalsky, Rebecca L., Cullen, Bryan R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985621/ https://www.ncbi.nlm.nih.gov/pubmed/24464996 http://dx.doi.org/10.1093/nar/gkt1393 |
Ejemplares similares
-
Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC
por: Salomon, William, et al.
Publicado: (2010) -
A role for human Dicer in pre-RISC loading of siRNAs
por: Sakurai, Kumi, et al.
Publicado: (2011) -
siRNAs targeted to certain polyadenylation sites promote specific, RISC-independent degradation of messenger RNAs
por: Vickers, Timothy A., et al.
Publicado: (2012) -
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
por: Castanotto, Daniela, et al.
Publicado: (2007) -
ADAR mediates differential expression of polycistronic microRNAs
por: Chawla, Geetanjali, et al.
Publicado: (2014)