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Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data
Chromosomes are not positioned randomly within a nucleus, but instead, they adopt preferred spatial conformations to facilitate necessary long-range gene–gene interactions and regulations. Thus, obtaining the 3D shape of chromosomes of a genome is critical for understanding how the genome folds, fun...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985632/ https://www.ncbi.nlm.nih.gov/pubmed/24465004 http://dx.doi.org/10.1093/nar/gkt1411 |