Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

Gene regulatory interactions underlying the early stages of non-genotoxic carcinogenesis are poorly understood. Here, we have identified key candidate regulators of phenobarbital (PB)-mediated mouse liver tumorigenesis, a well-characterized model of non-genotoxic carcinogenesis, by applying a new co...

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Detalles Bibliográficos
Autores principales: Luisier, Raphaëlle, Unterberger, Elif B., Goodman, Jay I., Schwarz, Michael, Moggs, Jonathan, Terranova, Rémi, van Nimwegen, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985636/
https://www.ncbi.nlm.nih.gov/pubmed/24464994
http://dx.doi.org/10.1093/nar/gkt1415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985636/
https://www.ncbi.nlm.nih.gov/pubmed/24464994
http://dx.doi.org/10.1093/nar/gkt1415

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