Aptamer-guided gene targeting in yeast and human cells

Gene targeting is a genetic technique to modify an endogenous DNA sequence in its genomic location via homologous recombination (HR) and is useful both for functional analysis and gene therapy applications. HR is inefficient in most organisms and cell types, including mammalian cells, often limiting...

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Detalles Bibliográficos
Autores principales: Ruff, Patrick, Koh, Kyung Duk, Keskin, Havva, Pai, Rekha B., Storici, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985672/
https://www.ncbi.nlm.nih.gov/pubmed/24500205
http://dx.doi.org/10.1093/nar/gku101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985672/
https://www.ncbi.nlm.nih.gov/pubmed/24500205
http://dx.doi.org/10.1093/nar/gku101

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