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Improved search heuristics find 20 000 new alignments between human and mouse genomes

Sequence similarity search is a fundamental way of analyzing nucleotide sequences. Despite decades of research, this is not a solved problem because there exist many similarities that are not found by current methods. Search methods are typically based on a seed-and-extend approach, which has many v...

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Detalles Bibliográficos
Autores principales: Frith, Martin C., Noé, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985675/
https://www.ncbi.nlm.nih.gov/pubmed/24493737
http://dx.doi.org/10.1093/nar/gku104