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Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain
Developmental stage-specific expression of the β-type globin genes is regulated by many cis- and trans-acting components. The adult β-globin gene contains an E-box located 60 bp downstream of the transcription start site that has been shown to bind transcription factor upstream stimulatory factor (U...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985677/ https://www.ncbi.nlm.nih.gov/pubmed/24497190 http://dx.doi.org/10.1093/nar/gku107 |