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Unique Effect of Cu(II) in the Metal-Induced Amyloid Formation of β-2-Microglobulin
[Image: see text] β-2-Microglobulin (β2m) forms amyloid fibrils in the joints of patients undergoing hemodialysis treatment as a result of kidney failure. In the presence of stoichiometric amounts of Cu(II), β2m self-associates into discrete oligomeric species, including dimers, tetramers, and hexam...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985682/ https://www.ncbi.nlm.nih.gov/pubmed/24450572 http://dx.doi.org/10.1021/bi4016583 |