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Unique Effect of Cu(II) in the Metal-Induced Amyloid Formation of β-2-Microglobulin

[Image: see text] β-2-Microglobulin (β2m) forms amyloid fibrils in the joints of patients undergoing hemodialysis treatment as a result of kidney failure. In the presence of stoichiometric amounts of Cu(II), β2m self-associates into discrete oligomeric species, including dimers, tetramers, and hexam...

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Detalles Bibliográficos
Autores principales:	Dong, Jia, Joseph, Crisjoe A., Borotto, Nicholas B., Gill, Vanessa L., Maroney, Michael J., Vachet, Richard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985682/ https://www.ncbi.nlm.nih.gov/pubmed/24450572 http://dx.doi.org/10.1021/bi4016583

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