Concise Enantiospecific Total Synthesis of Tubingensin A

[Image: see text] We report the enantiospecific total synthesis of (+)-tubingensin A. Our synthesis features an aryne cyclization to efficiently introduce the vicinal quaternary stereocenters of the natural product and proceeds in only nine steps (longest linear sequence) from known compounds.

Detalles Bibliográficos
Autores principales: Goetz, Adam E., Silberstein, Amanda L., Corsello, Michael A., Garg, Neil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985696/
https://www.ncbi.nlm.nih.gov/pubmed/24524351
http://dx.doi.org/10.1021/ja501142e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985696/
https://www.ncbi.nlm.nih.gov/pubmed/24524351
http://dx.doi.org/10.1021/ja501142e

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