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Amino Acid Signature Enables Proteins to Recognize Modified tRNA

[Image: see text] Human tRNA(Lys3)(UUU) is the primer for HIV replication. The HIV-1 nucleocapsid protein, NCp7, facilitates htRNA(Lys3)(UUU) recruitment from the host cell by binding to and remodeling the tRNA structure. Human tRNA(Lys3)(UUU) is post-transcriptionally modified, but until recently,...

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Detalles Bibliográficos
Autores principales: Spears, Jessica L., Xiao, Xingqing, Hall, Carol K., Agris, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985708/
https://www.ncbi.nlm.nih.gov/pubmed/24483944
http://dx.doi.org/10.1021/bi401174h