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Single-Molecule Fluorescence Using Nucleotide Analogs: A Proof-of-Principle
[Image: see text] Fluorescent nucleotide analogues, such as 2-aminopurine (2AP) and pyrrolo-C (PyC), have been extensively used to study nucleic acid local conformational dynamics in bulk experiments. Here we present a proof-of-principle approach using 2AP and PyC fluorescence at the single-molecule...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985717/ https://www.ncbi.nlm.nih.gov/pubmed/24803990 http://dx.doi.org/10.1021/jz4025832 |