Energy Landscape of the Michaelis Complex of Lactate Dehydrogenase: Relationship to Catalytic Mechanism

[Image: see text] Lactate dehydrogenase (LDH) catalyzes the interconversion between pyruvate and lactate with nicotinamide adenine dinucleotide (NAD) as a cofactor. Using isotope-edited difference Fourier transform infrared spectroscopy on the “live” reaction mixture (LDH·NADH·pyruvate ⇌ LDH·NAD(+)·...

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Detalles Bibliográficos
Autores principales: Peng, Huo-Lei, Deng, Hua, Dyer, R. Brian, Callender, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985751/
https://www.ncbi.nlm.nih.gov/pubmed/24576110
http://dx.doi.org/10.1021/bi500215a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985751/
https://www.ncbi.nlm.nih.gov/pubmed/24576110
http://dx.doi.org/10.1021/bi500215a

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