Cargando…

Total Synthesis of the Akuammiline Alkaloid Picrinine

[Image: see text] We report the first total synthesis of the complex akuammiline alkaloid picrinine, which was first isolated nearly five decades ago. Our synthetic approach features a concise assembly of the [3.3.1]-azabicyclic core, a key Fischer indolization reaction to forge the natural product’...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Joel M., Moreno, Jesus, Boal, Ben W., Garg, Neil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985766/
https://www.ncbi.nlm.nih.gov/pubmed/24597784
http://dx.doi.org/10.1021/ja501780w