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Synthesis and Biological Evaluation of Bis-CNB-GABA, a Photoactivatable Neurotransmitter with Low Receptor Interference and Chemical Two-Photon Uncaging Properties

[Image: see text] Photoactivatable “caged” neurotransmitters allow optical control of neural tissue with high spatial and temporal precision. However, the development of caged versions of the chief vertebrate inhibitory neurotransmitter, γ-amino butyric acid (GABA), has been limited by the propensit...

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Detalles Bibliográficos
Autores principales: Shi, Diana D., Trigo, Federico F., Semmelhack, Martin F., Wang, Samuel S.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985807/
https://www.ncbi.nlm.nih.gov/pubmed/24422544
http://dx.doi.org/10.1021/ja411082f