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Nuclear Magnetic Resonance Studies of an N(2)-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations

[Image: see text] The dimensions and arrangements of aromatic rings (topology) in adducts derived from the reactions of polycyclic aromatic hydrocarbon (PAH) diol epoxide metabolites with DNA influence the distortions and stabilities of double-stranded DNA, and hence their recognition and processing...

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Detalles Bibliográficos
Autores principales: Rodríguez, Fabián A., Liu, Zhi, Lin, Chin H., Ding, Shuang, Cai, Yuqin, Kolbanovskiy, Alexander, Kolbanovskiy, Marina, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985812/
https://www.ncbi.nlm.nih.gov/pubmed/24617538
http://dx.doi.org/10.1021/bi4017044