Prospecting for Unannotated Enzymes: Discovery of a 3′,5′-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily

[Image: see text] In bacteria, 3′,5′-adenosine bisphosphate (pAp) is generated from 3′-phosphoadenosine 5′-phosphosulfate in the sulfate assimilation pathway, and from coenzyme A by the transfer of the phosphopantetheine group to the acyl-carrier protein. pAp is subsequently hydrolyzed to 5′-AMP and...

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Detalles Bibliográficos
Autores principales: Cummings, Jennifer A., Vetting, Matthew, Ghodge, Swapnil V., Xu, Chengfu, Hillerich, Brandan, Seidel, Ronald D., Almo, Steven C., Raushel, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985815/
https://www.ncbi.nlm.nih.gov/pubmed/24401123
http://dx.doi.org/10.1021/bi401640r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985815/
https://www.ncbi.nlm.nih.gov/pubmed/24401123
http://dx.doi.org/10.1021/bi401640r

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